International Dermatology Conference: Skin and Body November 26-27, 2018 Amsterdam, Netherlands

Biography:

Clemens Esche is a board-certified dermatologist who graduated from The Johns Hopkins dermatology program and held assistant professor appointments at the University of Pittsburgh, the Mayo Clinic and at The Johns Hopkins University. Dr. Esche founded The Beautiful Skin Institute PLLC in Herndon, VA, in 2016. He has received more than 10 academic awards for his pioneering research and has authored more than 70 publications. He was recognized with the Patient’s Choice Award in 2013 and became the National Winner of the Doctor’s Choice Award in 2014 and again in 2015. Dr. Esche treats adult, pediatric and cosmetic patients and specializes in minimally invasive cosmetic procedures with little to zero downtime.

Abstract:

Inflammation is the single greatest reason for acne scar development. Consequently, the extent of scarring is associated with acne severity and delay in treatment. Each scar is different and therefore requires a customized approach. Acne scars are currently classified into 3 different types: ​(i) atrophic, (ii) hypertrophic and ​(iii) keloidal​. A net destruction of collagen in the dermis results in ​atrophic​ scarring. It can be further ​classified as ​ice-pick​ (narrow and deep, 60%), ​boxcar​ (1.5-4 mm wide, 25%) or ​rolling​ (​15​%). Less commonly, there is a net gain of collagen that results in ​hypertrophic​ or ​keloidal ​scars. Ice-pick (deep pit) scars are frequently the most severe, and, unfortunately, represent around 2/3 of cases. ​Fraxel or CO2 laser treatment ​have been considered the gold standard until recently​. ​However​, fractional radiofrequency and also the Chemical Reconstruction of Skin Scars (CROSS) technique tend to be superior to even the most advanced fractional laser for the treatment of ice pick and deep scarring. They also tend to work well for boxcar and deep rolling scars. Four treatments at monthly intervals will serve many patients well. ​ An added benefit is the shorter recovery time compared with Fraxel laser. TCA CROSS involves a high-strength TCA peel (50-100%) applied to the base of the scar to ablate the epithelial wall and to promote dermal remodeling. The degree of clinical improvement is proportional to the number of sessions. Hypertrophic and keloidal scars can be injected with corticosteroids, 5-fluorouracil, bleomycin or verapamil. Alternatives include silicone dressings and cryotherapy. Freezing from within with cryoshape is advocated periodically. Numerous 2017 publications challenge the cosmetic procedural delay following oral isotretinoin therapy. An algorithmic approach summarizes the updated recommendations.

Biography:

Frien Refla Syarif has completed her MD degree from Trisakti University, Jakarta, Indonesia. She took Dermatology and Venereology Residency Program in Andalas University, Padang, Indonesia, graduated in 2016. The title of the thesis she took was about melasma. Dr. Refla has published several scientific papers in the national dermatology journal. Although in this moment is just her second year to be a Dermatologist, she has been a speaker for several times in domestic and national symposiums, and spoke about dermatology aesthetics in accordance to her passion. Dr. Refla has also been a keynote speaker several times in the national online newspaper.

Abstract:

Melasma is an acquired pigmentary disorder and characterized by symmetrical hyperpigmented macules and patches on the sun exposed area especially on  the face. It is one of the most common skin problem and widely occur in women. This hyperpigmentation disorder commonly occurs in Fitzpatrick skin types III to VI that can causes cosmetic disfigurement and leads to psychological problems. Its pathogenesis is not yet fully understood but the common risk factors for melasma include ultraviolet exposure, pregnancy, oral contraceptives, thyroid hormones, cosmetics, phototoxic medications, anticonvulsant drugs and genetic factor. Most recently data supported that pathogenesis of melasma involves vascular growth factors. Although various treatments are available for melasma, it remains a difficult condition to treat because pigment formation is highly complex. A wide variety of treatments include hydroquinone, tretinoin, kojic acid, azelaic acid, glycolic acid, arbutin, niacinamide, tranexamic acid, laser, broad spectrum sunscreen and sun avoidance have been suggested to be a pigmentation control agents. In recent times, platelet rich plasma (PRP) is fetching attention in aesthetic medicine with fewer side effects and could be a promising treatment options for melasma. Apart from topical treatments, oral medications are also widely developed to improve melasma and may provide as well for the treatment options for overall hyperpigmentation cases.

Biography:

Terri holds a Bachelor of Science (Immunology & Microbiology), a post-graduate Diploma of Formulating Chemistry, and a Diploma of Education (Biology & Senior Science). She is a world recognised formulator, lecturer and author in the field of cosmetic science. As the founder and formulator of Synergie Skin, Terri Vinson is dedicated to creating highly active cosmeceuticals and functionally protective mineral makeup. In accordance with her trademarked ‘Clean Science’ philosophy, she is dedicated to formulating safe and ethical products that protect, change, and nurture skin and promote long-term dermal health.

Abstract:

Introduction: The skin is the largest organ of the body and in constant contact with both the internal and external environment. The impact of environmental pollution and solar radiation (UV,IR and HEV) are the major contributoirs to cellular damage, free radical formation and enviroageing. Until recently the aesthetics industry has been solely focused on the harmful effecs of ultraviolet wavelenghts of radiation only. It is universally accepted that UVA and UVB protection is mandatory. However, we are now looking beyond the UV sprectum at the negative impact of infrared light and high energy visible light (in particular blue light) and the potentially damaging interaction with epidemal and dermal cells. Moreover, the impact of urban pollution is now recognised as a significant factor contributing to cellular inflammation and extrinsic ageing. This presentation investigates the impact of urban pollution and radiation beyond UV on th viability and function of human skin cells.

Discussion: (1) Dermal impact of environmental pollution (a) Discussion of cellular effects of PM2.5 and heavy metals, (b) Novel new ingredients to protect fom pollution damage, (c) Supporting In vivo and in vitro clinical data.(2) Discussion of Infrared (IR) light and effect on human cells (a) Discussion of novel new topical to comabat IR dermal damage,  (b) Supporting In vivo and in vitro clinical data. (3) Overview of UVA and UVB damage and impact on human skin cells (a) Mineral sunscreen protection, (b) Supporting in vivo data. (4) Impact of HEV (High energy visible) blue light on  deraml viability, (a) Environmental Protection from Blue light, (b) New evidence supporting the presence of light receptors in skin. (5) Protective cosmeceutical ingredients to mitigate enviroageing

Conclusion:  Science is now able to look beyond UV into enviroageing and and discover novel ingredients to combat environmentally based cellular damage and inflammation.

Biography:

Abstract: